How DOES
Poly-MVA Work?
to understand the benefits and features of poly-MVA
We need to start with “Mitochondria and Metabolism”
Mitochondria and our CELLS
Mitochondrial Function and its impact in Cancer Cell Development
“Decades ago, (Nobel Prize Winning Scientist) Otto Warburg observed that cancers ferment glucose in the presence of oxygen, suggesting that defects in mitochondrial respiration may be the underlying cause of cancer.
Mitochondria NOT only supply energy, provide building blocks for new cells, and Control redox homeostasis Oncogenic signaling Innate immunity and Apoptosis (programmed cell death). Thus, mitochondria play a central and multi-functional role in malignant tumor progression, and targeting mitochondria provides therapeutic opportunities.”
Facts about Mitochondria
- Mitochondria function as batteries that produce more than 90% of the energy of the body.
- Mitochondria most prevelant in organs such as your heart, liver, muscles and brain.
- 40% of each heart muscle cell and 25% of each liver cell are made up of mitochondria.
About mitochondrial disorders
- Every 30 minutes, a child is born who will develop a mitochondrial disorder or disease by age 10.
- Mitochondrial disease affects at least 1 in every 4,300 people globally.
- When mitochondria fail, less and less energy is generated within cells. –*This will eventually lead to cell damage, fatigue, disease and ultimately death.
- Mitochondrial disease is a chronic disorder that occurs when there is NOT enough energy for that cell, tissue or organ to function.
- Physicians and researchers have known about mitochondrial disease for over 30 years and we are only really hearing about this recently.
- Search Mitochondria and any disease or illness.
Mitochondrial dysfunction repair: the process starts with Nutrition, Detoxification-Removing toxins and chemicals and supplements that can target and support them specifically.
Mitochondria’s direct link to Good and Bad Health
These brief Videos will help the viewer to better understand the direct and primary role that Mitochondrial Dysfunction plays in the “initiation and progression” of Cancer & Disease. By restoring, repairing and returning Mitochondria to a healthy normal status we can either return the cell to proper function or to turn the cell off through apoptosis, normal cell death.
“Damaged Mitochondria” linked to many health issues.
“Mitochondrial Dysfunction” and Cancer Metabolism
BONUS VIDEO
TED talk where Dr. D’Agostino talks about Metabolism, The Warburg effect (oxygen changes in cells) and Dr. Seyfried research in Metabolism.
Start watching at 5:51 in the Video
Starving cancer: Dominic D’Agostino at TEDx TampaBay
Dr. D’Agostino is an Assistant Professor at the University of South Florida College Of Medicine, Molecular Pharmacology & Physiology where he develops and tests metabolic therapies, including alternative energy substrates and ketogenic agents for neurological disorders, cancer and wound healing. While studying the effects of gasses on the brains of Navy Seal divers, he developed an approach for metabolically starving cancer cells ….. an alternative and an adjunct to chemotherapy, surgery, or radiation. |
SECTION #1
Mitochondrial Function Difference
Healthy/Normal Cell vs Cancer/Abnormal Cell
HEALTHY CELL
Aerobic “Normal Oxygen” Respiration
NORMAL MITOCHONDRIAL FUNCTION
* Mitochondria generate “high/energy” for the Healthy Cells and normal cellular function
NORMOXIC STATE
Normal “oxygen and high energy (electron) production” within the
Mitochondria allows cell to perform all of its cellular functions!
CANCER CELL
Anaerobic “Low Oxygen” Respiration
IMPAIRED/ALTERED MITOCHONDRIAL FUNCTION
* Mitochondria “low/altered energy state”, unable to perform normal cellular function
HYPOXIC STATE
Dramatically reduced “oxygen and low energy (electron) production” causes cell dysfunction & a switch to anaerobic metabolism.
SECTION #2
Poly-MVA accepts and donates/shuttles electrons directly to the Mitochondrial Complexes 1-4
Electron receptor/Cell Protector and Electron Donor/Mitochondrial support
THE Power of Poly-MVA
The Oxygen Radical Absorbance Capacity (known as the ORAC value or score) is a method developed by scientists at the National Institute of Health and Aging (NIH) to measure the antioxidant capacity of different foods and compounds.
Whilst the exact relationship between the ORAC value of nutrients and its health benefit has not been fully established, it is generally understood that compounds with higher ORAC scores have greater antioxidant capacity, and more effectively neutralize/scavenge harmful free radicals.
According to the free-radical theory of ageing and disease, a high antioxidant intake from foods/compounds, will slow/balance the oxidative processes and free radical damage that contributes to age-related degeneration and disease.
ORAC Value Comparisons
* Brunswick Labs, Wareham, MA
| expressed as Trolox equivalent per gram) | ||||||||
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SECTION #3
Poly-MVA Shuttles Electrons up regulating the Mitochondria:
“Healthy Cells” receive benefit/energy – “Cancer Cells” suffer damage/apoptosis
"Positive Impact" on a NORMAL CELL
Aerobic "Normal Oxygen" Respiration
POLY-MVA donates Electrons to Mitochondria
* Poly-MVA helps Mitochondria to generate “energy” to maintain , restore, repair and revitalize the Healthy Cell
NORMOXIC STATE
Poly-MVA's ability to re-supply the mitochondria with electrons, allows the cell to maintain "Energy and Optimal" Mitochondrial Function!
"Negative Impact" on a CANCER CELL
Anaerobic "Low Oxygen" Respiration
POLY-MVA donates Electrons to Mitochondria
* Mitochondria in this state, create oxygen radicals that either return the cell to normalcy or turn on the apoptotic cascade, cell death.
HYPOXIC STATE
Mitochondria in Cancer Cells are limited and not able to accept & redistribute the "electrons" which damages the cell and initiates Apoptosis!
NORMAL HOUSE
Represents Healthy/Normal Cell
CANCER HOUSE
Represents Cancer/Abnormal Cell
Electrical Distribution in a ‘House’ – – – COMPARED TO – – – Electrical Distribution in a ‘Human Cell’
–Poly-MVA targets MITOCHONDRIA providing
RESTORATION-REPAIR-RECOVERY for Healthy Cells – ENERGY to get the job DONE
Poly-MVA repairs or shuts down the “Aerobic/Cancer” Cells
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